Contributed By: Cliff Hobbs [MVP ConfigMgr/ SMS]
Yes the Service Pack (SP) 2 or SP3 version of the 32-bit Advanced Client is supported on the following x64-based Operating Systems (OSs):

Windows XP Professional x64 Edition Windows Server 2003 Standard x64 Edition Windows Server 2003 Enterprise x64 Edition Windows Server 2003 Datacenter x64 Edition Windows Server 2003, Enterprise Edition SP1 for Itanium-based Systems Windows Server 2003, Datacenter Edition SP1 for Itanium-based Systems Windows Vista x64

The Legacy Client is NOT supported on a 64-bit OS.

There are some important things to note though:

• The Advanced Client will run in 32-bit mode on these platforms - there is no native 64-bit SMS 2003 Client

• SMS 2003 SP3 adds a new class "Add Remove Programs (64)" which allows Software Inventory to collect information relating to 64-bit apps running on 64-bit computers

• The Inventory Tool for Microsoft Updates (ITMU) shipped with SMS 2003 SP3 can be used for detection and deployment of Microsoft security updates for 64-bit operating systems.

• The 64-bit Advanced Client is installed in the "<systemroot>\windows\syswow64\ccm" directory

• To see the SMS icons in Control Panel you need to click "View x86 Control Panel Icons"

To see other SMS Design related FAQs click here.